OsseoSeal (private label brand of Ossguide) is a resorbable collagen membrane derived from purified porcine pericardium. This membrane was designed to provide superior barrier function, while maintaining ideal handling characteristics. If you have any questions about OsseoSeal membrane, please review our FAQ below.
What is the difference between OsseoSeal(OssGuide) and Bio-Gide?
According to the FDA 510-K submission for OssGuide, the FDA concluded that both products are substantially equivalent. The primary difference between OssGuide and Bio-Gide is that OssGuide is manufactured from Porcine pericardium, while Bio-Gide is made from Porcine peritoneum.
How should OsseoSeal (Ossguide) be secured in place?
The membrane may be secured in place with sutures, tacks, or by means of sufficient contact with the mucoperiosteal flap to avoid displacement and micro motion during healing. To facilitate proper healing, ensure that there is tension-free primary closure of the soft tissue flap covering the membrane.
What is the difference between OsseoSeal and Neomem FlexPlus
Both OsseoSeal and Neomem Flexplus are manufactured from porcine. As such, they both offer excellent handling and adaptation to various defects. The difference is simply that Neomem Flexplus is a chemically cross-linked membrane made from porcine peritoneum, while OsseoSeal is made from purified porcine pericardium and enhanced via Dehydrothermal (DHT) treatment, which is a physical crosslinking method. There is substantial controversy surrounding chemically cross-linked vs non cross-linked membranes, and the research is conflicting. Clinicians should opt to simply choose the membrane they feel most comfortable with. You can read more about OsseoSeal here: [OsseoSeal Placement](https://community.ddsgadget.com/t/placement-techniques-for-osseoseal-porcine-collagen-membrane/30)
